Written by Greg Jefferys, Hepatitis C Writer and Activist
Buying Generic Epclusa (Sofosbuvir 400 mg + Velpatasvir 100 mg) from India
What Is Generic Epclusa?
Licensed generic Epclusa is exactly the same as a brand-name Epclusa in its effectiveness, dosage and quality, as well as in the way it is taken. Generic Epclusa has the same benefits, side effects and cure rates as brand-name Epclusa, in fact generic Epclusa is identical to Epclusa except in name and the colour of the pill.
The Hepatitis C medication Epclusa is the combination of two drugs, Sofosbuvir 400 mg and Velpatasvir 100mg. These two drugs are called Direct Acting Antivirals (DAAs) because they act directly on the Hepatitis C virus by blocking its ability to replicate. Epclusa is a pan-genotype Hep C drug, which means that it is effective against all genotypes of Hepatitis C. Epclusa is also the most effective Hepatitis C treatment for patients with high levels of liver fibrosis or liver cirrhosis.
Epclusa is made by the USA based pharmaceutical company GILEAD SCIENCES. In 2017 Gilead reached agreements with several of India’s largest pharmaceutical companies to manufacture a generic version of Epclusa so that people living in situations of poverty could access cheaper Hep C treatment. The generic Epclusa made in India is an exact replica of brand Epclusa except for the colour of the pill and the imprint on the pill. Generic Epclusa is chemically identical to brand Epclusa. Generic Epclusa also has exactly the same cure rates as brand Epclusa
What is the price of generic Epclusa?
The price of generic Epclusa Epclusa from India is US$850 for a 12 week treatment including shipping and shipping insurance. Shipping is by express airmail and your Epclusa can be tracked online. Delivery takes between 7 and 10 days, depending on which country you live in.
Buying Generic Epclusa Online
Buying Epclusa online from India is surprisingly simple. You simply need to send us any medical report that shows that you have Hepatitis C. On receipt of this report our doctor will write your prescription. Then we just need your shipping details and payment.
Once we have these three things your generic Epclusa will be shipped within 48hours and we will send you the tracking number.
Remember, you will be receiving Gilead Sciences authorized generic Epclusa which is an exact replica of Epclusa except for the colour of the pill and the price.
Genuine Generic Epclusa
Greg Jefferys’ Hep C Buyers Club makes buying generic Epclusa online safe and simple. To buy genuine licensed generic Epclusa you simply need to send a medical report or test result that shows that you have Hepatitis C. Our doctor inspects the medical report and uses it to write a prescription for generic Epclusa. Once this is done it is simply a matter of shipping and starting treatment.
If you have questions about getting generic Epclusa from India simply send an email to the Hep C Buyers’ Club and they will assist you with everything you need to know about buying generic Epclusa online. Email now by clicking here.
For many people, unless they have good health insurance or live in a country that provides free health cover, the retail cost of Epclusa is around US$80,000 but if you get GILEAD’s licensed generic Epclusa the cost is only US$850 for 12 weeks of treatment including shipping.
The Short Story on Generic Epclusa
Gilead licensed generic Epclusa became available from India in May 2017. Part of the reason for this was that India did not initially recognize GILEAD’s patent for Sofosbuvir, the main ingredient of Epclusa, meaning that Indian pharmaceutical companies could manufacture Sofosbuvir based Hep C treatments without paying GILEAD any royalties and sell them in any country where GILEAD had not been granted patents.
This would have meant huge losses for GILEAD and also created a highly competitive marketplace. So instead GILEAD reached agreements with Indian drug manufacturers.
Gilead’s agreement with licensed Indian manufacturers of generic Epclusa required that GILEAD handed over all the manufacturing technology for Epclusa, so that the generic Epclusa would be exactly identical to the brand Epclusa. In return, GILEAD required that the quality and ingredients of the generic Epclusa be EXACTLY the same as brand Epclusa.
Licensed manufacturers of generic Epclusa pay GILEAD a royalty for all generic Epclusa sold.
Is Generic Epclusa as Effective as Brand Epclusa
Generic Epclusa gives exactly the same cure rates as brand Epclusa. Numerous independent trials have been conducted using generic Epclusa and all of these trials came up with the same results. Generic Epclusa has exactly the same cure rates as brand Epclusa. Click this link to see results of independent studies of generic Epclusa cure rates
How Much Does Generic Epclusa Cost?
The cost for 12 weeks of generic Epclusa from India will vary depending on the brand of generic Epclusa and also your treatment requirements.
To order generic Epclusa, such as VelaSof or MyHep All, from India please email me for details.
Our Hep C Buyers’ Club can organise shipment of generic Epclusa to most countries including the USA, Europe, Brazil, and just about every other country on Earth.
Epclusa offers a number of advantages to people with Hep C. Firstly Epclusa treats all genotypes of Hep C, this means that if you do not know which genotype of Hep C you have then using Epclusa will save you the cost of getting a genotype test. Epclusa is also generally considered to be the most effective treatment for Hep C Genotype 3 though it only offers a cure rate that is 1% higher than Sofosbuvir + Daclatasvir.
To buy 12 weeks treatment of Gilead Licensed generic Epclusa for US$850 (including shipping costs) Please email me for details.
Remember that when you buy your Hep C medication through Greg Jefferys Buyers’ Club:
Delivery is 100% Guaranteed
Your medication is 100% insured against any loss or damage.
Your medication is made under license from GILEAD SCIENCES in FDA and WHO approved facilities.
There is a 100% Money Back Guarantee if you are not cured Hepatitis C.
(Guarantee is provided if you take the recommended treatment for your Hepatitis C based on accepted international standards)
The Long Story
Epclusa is made by GILEAD, the same company that manufactures Sovaldi (Sofosbuvir 400 mg) and Harvoni (Sofosbuvir 400 mg + Ledipasvir 90 mg).
Whilst Harvoni was, and still is, the optimum treatment for Hep C genotype 1 it is not the best treatment for all other genotypes of Hepatitis C, which, up until the release of Epclusa, were best treated by the combination of Sofosbuvir 400 mg + Daclatasvir 60 mg.
Because Hep C genotype 1 represents about 55% of all Hep C infections GILEAD had a large part of the market covered with Harvoni however it was missing out on profits from the other half of the market, which was G3 about 25% and G2 about 15%. So because GILEAD is all about profits it was worried it was not making any money out of G2 and G3.
So GILEAD put in a lot of work to find a drug combination based around Sofosbuvir that would work against all genotypes of Hep C.
That mission was completed with the arrival of Epclusa which is made of Sofosbuvir 400 mg + Velpatasvir 100 mg.
Whilst Epclusa is not any better for treating G1 than Harvoni it is equal to, or a little better than, Sofosbuvir + Daclatasvir for treating other genotypes of Hep C.
Recent research suggests that Sofosbuvir + Velpatasvir is only about 1% better than Sofosbuvir + Daclatasvir for treating Hep C genotype 3.
However, the big advantage of Epclusa is that a person does not need to know their genotype of Hep C to begin treating the virus because Epclusa will treat all genotypes of Hepatitis C thus removing the need to take the Hep C genotype test.
For a lot of people, this is a big saving in money terms because the test for genotype generally costs over US0.
Of course like all GILEAD products, with a price tag of around US,000 for 12 week’s treatment Epclusa, is grossly overpriced and out of the reach of most people who need treatment for chronic Hepatitis C.
Like all GILEAD products, the aim is to sell Epclusa at a price that maximizes profits and minimizes access, so Epclusa is only affordable to people with top level health insurance or living in wealthy countries that can afford to include it in their National Health Services.
For the other 100 million+ people with Hep C the generic Epclusa from India is a good option.
A Brief History of Generic Epclusa
Generic Epclusa from India
When Epclusa was released in the USA and Europe once again India entered into negotiations with GILEAD. This time to produce a licensed generic version of Epclusa. Because part of the license agreement is that the Indian manufacturers will have access to all of GILEAD’s intellectual property, including the technology for improving absorption of Velpatasvir, this means that the Indian generic Epclusa is identical to the GILEAD branded Epclusa.
As with Harvoni two Indian pharmaceutical companies are making the generic Epclusa, these are Natco and Hetero Pharmaceuticals.
Whilst both of these companies finalised licensing agreements with GILEAD to manufacture generic Epclusa late in 2016 the India government has been a little tardy in granting these companies permission to sell generic Epclusa in India.
This permission for Hep C Treatment licensing finally came through in April 2017 and the release date for the generic Epclusa to be available for sale in India was May 2017.
The price is somewhere around US$850 to US$1,600 for a 12 week treatment, depending on who you purchase from.
How Effective is Epclusa?
Epclusa is effective against all genotypes of Hepatitis C and is particularly useful for patients infected with Hepatitis C genotype 3 and also for patients who have liver cirrhosis.
Epclusa is much more effective than Mavyret if a patient has liver cirrhosis or high liver fibrosis levels.
If you have Hep C genotype 1 there is no real advantage in using Epclusa over Harvoni as both give the same cure rates.
If you have G2 than Sofosbuvir + Daclatasvir will be slightly more effective than Epclusa ( Sofosbuvir +Velpatasvir). The graph below compares Epclusa with Sofosbuvir + Daclatasvir for the treatment of Hep C genotype 3 and Hep C genotype 2. This study was of 5,400 patients from the Department of Veterans Affairs.
For the treatment of Genotype 3 Sofosbuvir + Velpatasvir is only very slightly better than Sofosbuvir + Daclatasvir but is a lot more expensive. For Genotype 3, whichever treatment is used it is wise to be considering doing more than the recommended 12 weeks to give optimum cure rates. If it were me I would do at least 16 weeks. Recent research shows that adding Ribavirin, which is often recommended, does not improve cure rates. Because Ribavirin is quite toxic it is often wise to avoid using it.
If you do not know what genotype of Hepatitis C you have and if you would have problems finding the US0 or more for the genotype test then Epclusa is a very good idea.
Another good reason for using Epclusa is that about 10% of people with Hepatitis C are infected with more than one genotype. By using Epclusa all genotypes will be treated. Though, again, treating with Sofosbuvir + Daclatasvir would give the same results.
Order Licensed Generic Epclusa Now
I hope this is information helpful to people. If you would like to order generic Epclusa online or need information about Epclusa please email me and I will help you. The cost will not be above US$850 for a 12 weeks treatment.