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Guidelines For Treating Hepatitis C

Here are some easy to read guidelines for Hepatitis C treatment

Simple Guidelines for Treating Hepatitis C

Once a person learns they have Hepatitis C the first thing that they want to know is how to cure Hep C.

Below are simple guidelines for the treatment of Hepatitis C. I have written these guidelines so they are easy to understand for anyone with Hep C.

If you wish for more detailed information on options for treating Hepatitis C then you are welcome to contact me directly or to join my Hepatitis C Support group on Facebook, the link is on this page.

 

If You Know the Genotype of Hepatitis C You are Infected With the following treatment guidelines will help. If you do not know the genotype of Hepatitis C you are infected with please read the suggestions at the end of this page.

 

Hepatitis C Genotype 1 Treatment Options:

Hepatitis C Genotype 1 can be treated with 12 weeks of:

  1. Sofosbuvir + Ledipasvir (Harvoni)
  2. Sofosbuvir + Daclatasvir
  3. Sofosbuvir + Velpatasvir (Epclusa)
  4. Glecaprevir + pibrentasvir (Mavyret)

In most situations, the Sofosbuvir based treatments will give a slightly higher cure rate, especially if the patient has cirrhosis of the liver or has failed previous treatment. For Genotype 1b Sofosbuvir + Daclatasvir will give a slightly higher cure rate than Harvoni.

Treating Hep C genotype 3

The latest research shows that Sofosbuvir + Velpatasvir (Epclusa) and Sofosbuvir + Daclatasvir both give essentially the same cure rates for Hep C genotype 2 and genotype 3.

Hepatitis C Genotype 2 Treatment Options:

Hepatitis C Genotype 2 can be treated with 12 weeks of:

  1. Sofosbuvir + Daclatasvir
  2. Sofosbuvir + Velpatasvir (Epclusa)
  3. Glecaprevir + pibrentasvir (Mavyret)

Hepatitis C Genotype 3 Treatment Options:

Whilst genotype 3 can be treated with 12 weeks treatment of the drug combinations listed below research has shown that longer treatment times will give higher cure rates for genotype 3. A 12 weeks treatment will give around a 92% cure rate lifting the treatment time will lift the cure rate with any of these Hep C medications:

  1. Sofosbuvir + Daclatasvir
  2. Sofosbuvir + Velpatasvir (Epclusa)
  3. Glecaprevir + pibrentasvir (Mavyret)

Hepatitis C Genotype 4 Treatment Options:

Hepatitis C Genotype 4 can be treated with 12 weeks of:

  1. Sofosbuvir + Ledipasvir (Harvoni)
  2. Sofosbuvir + Daclatasvir
  3. Sofosbuvir + Velpatasvir (Epclusa)
  4. Glecaprevir + pibrentasvir (Mavyret)

If you do not know the genotype of Hepatitis C

If you do not know the genotype of Hepatitis C you are infected with and cannot access the Hepatitis C genotype test you should use a “pan-genotype” treatment, which will cure all genotypes. Pan-genotype Hepatitis C treatments include:

  1. Sofosbuvir + Daclatasvir
  2. Sofosbuvir + Velpatasvir (Epclusa)
  3. Glecaprevir + pibrentasvir (Mavyret)

When 12 weeks treatment for a Hepatitis C infection is not long enough.

Below are the circumstances when 12 weeks treatment for Hep C is not long enough.

  1. If you have cirrhosis of the liver or a high fibrosis level.
  2. If you have failed a previous Hep C treatment.
  3. If you have Hepatitis C genotype 3.

 

 

 

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Greg Jefferys

Greg Jefferys

2 Comments

  •    Reply

    Hey Greg,

    Just got diagnosed yesterday, after having high liver enzymes, for 4 months, and misdiagnosed. It’s a bit overwhelming, was not expecting to hear this. There is so much info to process. Anyway I did join this group and that is a start. I live in Fl and lost my health insurance, it may be a huge problem for me. I do have an appt on the 24th Oct this facility is low cost….have to start somewhere. My biggest concern is the medications. How do they expect people to pay for them. I see people with insurance struggling with costs. Went to the pharm. websites, it is very sad indeed. Any suggestions would be helpful, I have been reading all your guidelines, and they are very helpful. Thanks for listening Best, Samantha

    •    Reply

      Hi Samantha
      I certainly understand the shock that you are going through: and the steep learning curve. I went through the same thing myself in 2014.
      Please email me and I will do whatever I can to assist you

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